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  • Reacties op een homeopathisch geneesmiddel. Om te kunnen bepalen of het homeopathische geneesmiddel een gunstige uitwering heeft, dienen we de ontstane reacties op het gegeven middel te beoordelen. Die kunnen variëren van een beginverergering, het opkomen van oude klachten (die doorgaans weer verdwijnen), het ontstaan van nieuwe klachten (zelden), een tijdelijke of blijvende verbetering tot algehele genezing. Aan de patiënt wordt gevraagd de veranderingen, zowel positieve als negatieve, bij te houden en eventueel aantekeningen te maken. Tijdens een vervolgconsult, meestal na 6-8 weken, worden de  reacties doorgenomen en bepaald of er met het gegeven homeopathisch geneesmiddel wordt doorgegaan, of een ander meer passend middel wordt gekozen.Zie website: beoordeling reacties
  • Recidiverende acute aandoeningen vallen onder de chronische ziekten. Voorbeelden hiervan zijn: recidiverende luchtweginfecties, terugkerende urineweg infecties, maar ook hooikoortsaanvallen en periodieke hoofdpijnen, zoals migraine. In deze gevallen dient, net als bij de behandeling van andere chronische zieken, het totaal aan klachten en symptomen van de hele patiënt het uitgangspunt te zijn voor de geneesmiddelkeus. Zo zal men een hooikoorts-patiënt het liefst buiten het hooikoorts seizoen constitutioneel behandelen.

    1. http://www.facultyofhomeopathy.org/research/
    2. Boas PJFV, Spagnuolo RS, Kamegasawa A, et al. Systematic reviews showed insufficient evidence for clinical practice in 2004: what about in 2011? The next appeal for the evidence-based medicine age. J Eval Clin Pract, 2013; 19(4):633-7 | PubMed
    3. Lewith GT. Funding for CAM. BMJ., 2007; 335(7627): 951. | PubMed
  • [1] Jacobs J, Jonas WB, Jiménez-Pérez M & Crothers D. Homeopathy for childhood diarrhea: combined results and metaanalysis from three randomized, controlled clinical trials. Pediatr. Infect. Dis. J., 2003;22:229–234 | PubMed[2] Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial. Pediatr Infect Dis J., 2001; 20(2): 177-83 | PubMed[3] Sinha MN, et al. Randomized controlled pilot study to compare Homeopathy and Conventional therapy in Acute Otitis Media. Homeopat. J. Fac. Homeopat., 2012; 101: 5–12 | PubMed[4] Wiesenauer M & Lüdtke R. A meta analysis of the homeopathic treatment of pollinosis with Galphimia glauca. Forsch. Komplementärmed., 1996; 3: 230-234 | PubMed[5] Reilly DT, Taylor MA, et al. Is homoeopathy a placebo response? Controlled trial of homoeopathic potency, with pollen in hayfever as model. Lancet, 1986; 2(8512): 881-886 | PubMed[6] Schneider B, et al. Treatment of vertigo with a homeopathic complex remedy compared with usual treatments – a meta-analysis of clinical trials, Arzneim.-Forschung, 2005; 55(1): 23-29 | PubMed
  • [1] Witt CM, Bluth M, Albrecht H, Weisshuhn TE, Baumgartner S, Willich SN. The in vitro evidence for an effect of high homeopathic potencies–a systematic review of the literature. Complement Ther Med., 2007; 15(2): 128-38 | PubMed[2] Davenas E, Beauvais F, Amara J, et al. Human basophil de-granulation triggered by very dilute antiserum against IgE. Nature, 1988; 333: 816–818 | PubMed[3] Ovelgönne JH, Bol AW, Hop WC, van Wijk R. Mechanical agitation of very dilute antiserum against IgE has no effect on basophil staining properties. Experientia, 1992; 48: 504–508 | PubMed [4] Hirst SJ, Hayes NA, Burridge J, et al. Human basophil degranulation is not triggered by very dilute antiserum against human IgE. Nature, 1993;366: 525–527 | PubMed[5] Belon P, Cumps J, Ennis M, et al. Inhibition of human basophil degranulation by successive histamine dilutions: results of a European multi-centre trial. Inflammation Research, 1999; 48 (Suppl 1): S17–18 | PubMed[6] Lorenz I, Schneider EM, Stolz P, et al. Sensitive flow cytometric method to test basophil activation influenced by homeopathic histamine dilution. Forschende Komplementärmedizin, 2003; 10: 316–324 | PubMed[7] Belon P, Cumps J, Ennis M, et al. Histamine dilutions modulate basophil activation. Inflammation Research, 2004; 53: 181–188 | PubMed[8] Harrer B. Replication of an experiment on extremely diluted thyroxine and
highland amphibians. Homeopathy, 2013;102(1):25-303 | PubMed[9] Endler P, Thieves K, Reich C, Matthiessen P, Bonamin L, Scherr C, Baumgartner S. Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study. Homeopathy, 2010; 99(1): 25-36 | PubMed | HRI Synopsis[10] Betti L, et al. Effectiveness of ultra high diluted arsenic is a function of succussion number as evidenced by wheat germination test and droplet evaporation method. Int J High Dilution Res, 2013; 12 (44): 127–128 | Full text
    1. NHS Digital: NHS Prescription Cost Analysis 2016
    2. Freedom of Information Act request to the Department of Health by the Faculty of Homeopathy. Cost was £11.89 million between 2005 and 2008
    3. BMJ Clinical Evidence, Efficacy Categorisations. 2017. Available from http://clinicalevidence.bmj.com/x/set/static/cms/efficacy-categorisations.html  [Accessed 25 Sept 2017]
    4. Spence D, Thompson E A, Barron S J. Homeopathic treatment for chronic disease: a 6-year university-hospital outpatient observational study. J Altern Complement Med, 2005; 5: 793-798 | PubMed
    5. Sharples F, van Haselen R, Fisher P. NHS patients’ perspective on complementary medicine. Complement Ther Med, 2003; 11: 243-248 | PubMed
    6. Grimaldi-Bensouda, L. et al. Benchmarking the burden of 100 diseases: results of a nationwide representative survey within general practices. BMJ Open, 2011; 1, e000215 | Full text
    7. Grimaldi-Bensouda, L. et al. Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008. PLoS One, 2014;9: e89990 | Full text
    8. Rossignol, M. et al. Impact of physician preferences for homeopathic or conventional medicines on patients with musculoskeletal disorders: results from the EPI3-MSD cohort. Pharmacoepidemiol. Drug Saf, 2012; 21: 1093–1101 | PubMed
    9. Grimaldi-Bensouda, L. et al. Who seeks primary care for sleep, anxiety and depressive disorders from physicians prescribing homeopathic and other complementary medicine? Results from the EPI3 population survey. BMJ Open, 2012; 2 | Full text 
  • [1] Macías-Cortés ED et al. Individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP study): a randomized, double-dummy, double-blind, placebo-controlled trial. PLoS One, 2015 ;10(3):e0118440 | Full text[2] Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration. PLoS Med, 2008; 5(2): e45 | Full text[3] Sinha, MN et al. Randomized controlled pilot study to compare Homeopathy and Conventional therapy in Acute Otitis Media. Homeopat. J. Fac. Homeopat., 2012; 101: 5–12 | PubMed[4] Haidvogl M. et al. Homeopathic and conventional treatment for acute respiratory and ear complaints: A comparative study on outcome in the primary care setting. BMC Complement and Altern Med, 2007; 7:7 | Full text[5] Schneider et al. Treatment of vertigo with a homeopathic complex remedy compared with usual treatments – a meta-analysis of clinical trials. Arzneim.-Forschung, 2005; 55(1): 23-29 | PubMed[6] Witt C, Keil T, Selim D, et al. Outcome and costs of homeopathic and conventional treatment strategies: a comparative cohort study in patients with chronic disorders. Complement Ther Med, 2005;13: 79-86 | PubMed
  • 1. Mathie RT et al. Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis. Systematic Reviews, 2014; 3: 142
 | Full text2. Kleijnen J, Knipschild P, ter Riet G. Clinical trials of homeopathy. BMJ, 1991302: 960 | PubMed
  • [1] Norn S. et al. [From willow bark to acetylsalicylic acid].[Article in Danish]. Dan Medicinhist Arbog., 2009;37:79-98 | Abstract[2] Bottling RM. Vane’s discovery of the mechanism of action of aspirin changed our understanding of its clinical pharmacology. Pharmacol Rep., 2010; 62(3):518-25 | Abstract | Full text
    • Zanasi A, Mazzolini M, Tursi F, Morselli-Labate AM, Paccapelo A, Lecchi M (2014). Homeopathic medicine for acute cough in upper respiratory tract infections and acute bronchitis: A randomized, double-blind, placebo-controlled trial. Pulmonary Pharmacology & Therapeutics; 27(1): 102–108. 
      H  HRI2
    • Voß HW, Michalsen A, Brünjes R (2018). Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough-A double-blind, placebo-controlled, clinical trial. Drug Research (Stuttg); 68(8): 444–449.
      CompHom          HRI2
  • Acute otitis media, acute middenoorontsteking. (HRI)                 3 pos RCT

    • Sinha, MN et al. Randomized controlled pilot study to compare Homeopathy and Conventional therapy in Acute Otitis Media. Homeopat. J. Fac. Homeopat., 2012; 101: 5–12 | PubMed                                                 HRI
    • Haidvogl M. et al. Homeopathic and conventional treatment for acute respiratory and ear complaints: A comparative study on outcome in the primary care setting. BMC Complement and Altern Med, 2007; 7:7 | Full text
    • Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial. Pediatr Infect Dis J., 2001; 20(2): 177-83 | PubMed                                                           HRI2

     

    • Bergemann SM, Bornhöft, Bloch D, Vogt-Frank C, Righetti M, Thurneysen A, Clinical Studies on the Effectiveness of Homeopathy for URTI/A (Upper Respiratory Tract Infections and Allergic Reactions). In Bornhöft G, Matthiessen PF (eds), Homeopathy in Healthcare – Effectiveness, Appropriateness, Safety, Costs. Springer, Berlin 2011.                                                                                                  Fac
    • Bellavite P, Ortolani R, Pontarollo F, et al. Immunology and homeopathy. 4. Clinical studies – Part 1. Evidence-based Complementary and Alternative Medicine: eCAM, 2006; 3: 293–301.                                                                                    Fac
  • 7 pos RCT, 1 meta-analyse, 1 systematische review 

    • Wiesenauer M & Lüdtke R. A meta analysis of the homeopathic treatment of pollinosis with Galphimia glauca. Forsch. Komplementärmed., 1996; 3: 230-234 | Link                                                                                                            EnkHom  Meta-analyse
    • Reilly DT, Taylor MA, et al. Is homoeopathy a placebo response? Controlled trial of homoeopathic potency, with pollen in hayfever as model. Lancet, 1986; 2(8512): 881-886 | PubMed                              EnkHom    HRI2
    • Reilly D, Taylor MA, Beattie NGM, Campbell JH, McSharry C, Aitchison TC, Carter R, Stevenson RD (1994). Is evidence for homeopathy reproducible? Lancet; 344: 1601–1606.                                                                                                             EnkHom   HRI2
    •  Taylor MA, Reilly D, Llewellyn-Jones RH, et al. Randomized controlled trials of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series. British Medical Journal, 2000; 321: 471–476.                   HRI2       Fac
    • Bellavite P, Ortolani R, Pontarollo F, et al. Immunology and homeopathy. 4. Clinical studies – Part 2. Evidence-based Complementary and Alternative Medicine: eCAM, 2006; 3: 397–409.            1 Systematische review   Fac
    • Aabel S, Laerum E, Dølvik S, Djupesland P (2000). Is homeopathic ‘immunotherapy’ effective? A double-blind, placebo-controlled trial with the isopathic remedy Betula 30c for patients with birch pollen allergy. British Homeopathic Journal; 89: 161–168.                                                        EnkHom    HRI2
      • Kim LS, Riedlinger JE, Baldwin CM, Hilli L, Khalsa SV, Messer SA, Waters RF (2005). Treatment of seasonal allergic rhinitis using homeopathic preparation of common allergens in the southwest region of the US: a randomized, controlled clinical trial. Annals of Pharmacotherapy; 39: 617–624.              EnkHom      HRI2
    • Wiesenauer M, Gaus W, Häussler S (1990). Behandlung der Pollinoisis mit Galphimia glauca. Eine Doppelblindstudie unter Praxisbedingungen [Treatment of pollinosis with the homeopathic preparation Galphimia glauca. A double-blind trial in clinical practice]. Allergologie13: 359–363.            EnkHom     HRI2
    • Naidoo P, Pellow J (2013). A randomized placebo-controlled pilot study of Cat saliva 9cH and Histaminum 9cH in cat allergic adults. Homeopathy; 102: 123–129.                                                                                                                           EnkHom  HRI2

     

  • Tveiten D, Bruseth S, Borchgrevink CF, Norseth J (1998). Effects of the homoeopathic remedy Arnica D30 on marathon runners: a randomized, double-blind study during the 1995 Oslo Marathon. Complementary Therapies in Medicine6: 71–74.                                                              HRI2

    • Brinkhaus B, Wilkens JM, Lüdtke R, et al. Homeopathic arnica therapy in patients receiving knee surgery: Results of three randomized double-blind trials. Complementary Therapies in Medicine, 2006; 14: 237–246.   

                                                                                                                                    EnkHom  Fac

    • Sorrentino L, Piraneo S, Riggio E, Basilicò S, Sartani A, Bossi D, Corsi F (2017). Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce post-operative seroma and bleeding in patients undergoing total mastectomyJournal of Intercultural Ethnopharmacology6(1): 1–8.                                                                           E                                                                                                                           EnkHom HRI2
    • Chaiet SR, Marcus BC (2016). Perioperative Arnica montana for reduction of ecchymosis in rhinoplasty surgery. Annals of Plastic Surgery76: 477–482.                                                                                                                    EnkHom  HRI2
    • Belon P, Banerjee A, Karmakar SR, Biswas SJ, Choudhury SC, Banerjee P, Das JK, Pathak S, Guha B, Paul S, Bhattacharjee N, Khuda-Bukhsh AR (2007). Homeopathic remedy for arsenic toxicity? Evidence-based findings from a randomized placebo-controlled double blind human trial. Science of the Total Environment; 384: 141-50.
      EnkHOm   HRI2
    • Khuda-Bukhsh AR, Pathak S, Guha B, Karmakar SR, Das JK, Banerjee P, Biswas SJ, Mukherjee P, Bhattacharjee N, Choudhury SC, Banerjee A, Bhadra S, Mallick P, Chakrabarti J, Mandal B (2005). Can homeopathic arsenic remedy combat arsenic poisoning in humans exposed to groundwater arsenic contamination? A preliminary report on first human trial. Evidence-Based Complementary and Alternative Medicine2: 537–548.
      EnkHom     HRI2
    • Atopische dermatitis
      2 pos RCT
      Mandal S, Ghosh S, Das AD, Biswas B, Palanisamy C, Guha N, Maiti S, Dutta S, Singh NK, Koley M, Saha S (2023). Double-Blind, Randomized, Placebo-Controlled Trial of Individualized Homeopathic Medicines in Atopic Dermatitis in Adults: A Replication Trial with 6 Months’ Follow-up. Homeopathy; 12(4):251-261. 
      IndHOm   HRI2
    • Merklinger S, Messemer C, Niederle S (1995). Ekzembehandlung mit cardiospermum halicacabum: Cardiospermum-Salbe und Salbengrundlage im Halbseitenvergleich – eine kontrolllerte Studie [Treatment of eczema with Cardiospermum halicacabum: Cardiospermum ointment and the ointment vehicle – a controlled study]. Zeitschrift für Phytotherapie; 16: 263-266.
      EnkHom   HRI2
    • Mandal S, Ghosh S, Das AD, Biswas B, Palanisamy C, Guha N, Maiti S, Dutta S, Singh NK, Koley M, Saha S (2023). Double-Blind, Randomized, Placebo-Controlled Trial of Individualized Homeopathic Medicines in Atopic Dermatitis in Adults: A Replication Trial with 6 Months’ Follow-up. Homeopathy; 12(4):251-261. 
      IndHOm   HRI2
    • Merklinger S, Messemer C, Niederle S (1995). Ekzembehandlung mit cardiospermum halicacabum: Cardiospermum-Salbe und Salbengrundlage im Halbseitenvergleich – eine kontrolllerte Studie [Treatment of eczema with Cardiospermum halicacabum: Cardiospermum ointment and the ointment vehicle – a controlled study]. Zeitschrift für Phytotherapie; 16: 263-266.
      EnkHom   HRI2
    • Mandal S, Ghosh S, Das AD, Biswas B, Palanisamy C, Guha N, Maiti S, Dutta S, Singh NK, Koley M, Saha S (2023). Double-Blind, Randomized, Placebo-Controlled Trial of Individualized Homeopathic Medicines in Atopic Dermatitis in Adults: A Replication Trial with 6 Months’ Follow-up. Homeopathy; 12(4):251-261.
      IndHOm   HRI2
    • Merklinger S, Messemer C, Niederle S (1995). Ekzembehandlung mit cardiospermum halicacabum: Cardiospermum-Salbe und Salbengrundlage im Halbseitenvergleich – eine kontrolllerte Studie [Treatment of eczema with Cardiospermum halicacabum: Cardiospermum ointment and the ointment vehicle – a controlled study]. Zeitschrift für Phytotherapie; 16: 263-266.
      EnkHom   HRI2
    • Shukla P, Nayak C, Baig MQ, Misra P (2020). Effects of pre-defined homoeopathic medicines to mitigate adverse dermatological effects of radiotherapy and vomiting of chemotherapy in breast carcinoma: A randomised, double-blind, placebo-controlled, pilot trial in the context of usual care. Indian J Res Homoeopathy; 14: 189-199.                                    HRI2

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      Oberbaum M, Yaniv I, Ben-Gal Y, Stein J, Ben-Zvi N, Freedman LS, Branski D (2001). A randomized, controlled clinical trial of the homeopathic medication Traumeel S in the treatment of chemotherapy-induced stomatitis in children undergoing stem cell transplantation. Cancer; 92: 684–690.  HRI2 
  • Qutubuddin M, Murty Singh S, Nayak C, Koley M, Saha S (2019). Efficacy of individualized homeopathy in bronchial asthma in adults: Double-blind, randomized, placebo-controlled, clinical trial in the context of usual care. Advances in Integrative Medicine; 6(2): 58–65.                            IndHom   

  • Weatherley-Jones E, Nicholl JP, Thomas KJ, Parry GJ, McKendrick MW, Green ST, Stanley PJ, Lynch SP (2004). A randomized, controlled, triple-blind trial of the efficacy of homeopathic treatment for chronic fatigue syndrome.  Journal of Psychosomatic Research; 56: 189–197.  
    EnkHom   HRI2

    • Grimaldi-Bensouda, L. et al. Who seeks primary care for sleep, anxiety and depressive disorders from physicians prescribing homeopathic and other complementary medicine? Results from the EPI3 population survey. BMJ Open, 2012; 2 | Full text                      
      Cohort studie
    • Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration. PLoS Med, 2008; 5(2): e45 | Full text
    • Macías-Cortés ED et al. Individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP study): a randomized, double-dummy, double-blind, placebo-controlled trial. PLoS One, 2015 ;10(3):e0118440 | Full text   
      HRI2

     

  • Adi BS, Vangani A, Siva Rami Reddy E. Effect of Syzygium cumini in type 2 diabetes mellitus by assessing glycosylated haemoglobin and blood glucose levels: a double blind randomized controlled trial (2020). Journal of Global Trends in Pharmaceutical Sciences; 11(4): 85468551.          EnkHom  HRI2

    • Jacobs J, Jonas WB, Jiménez-Pérez M & Crothers D. Homeopathy for childhood diarrhea: combined results and metaanalysis from three randomized, controlled clinical trials. Pediatr. Infect. Dis. J., 2003;22:229–234 | PubMed HRI2
    • Jacobs J, Jimenez LM, Malthouse S, Chapman E, Crothers D, Masuk M, Jonas WB (2000). Homeopathic treatment of acute childhood diarrhoea: results from a clinical trial in Nepal. Journal of Alternative and Complementary Medicine; 6: 131–139.                                                                                                                 IndHom   HRI2
    • Jacobs J, Jimenez LM, Gloyds SS, Gale JL, Crothers D (1994). Treatment of acute childhood diarrhea with homeopathic medicine; a randomized clinical trial in Nicaragua. Pediatrics; 93: 719–725.                                                          IndHom  HRI2
  • Ghosh S, Ravindra RK, Modak A, Maiti S, Nath A, Koley M, Saha S. Efficacy of individualized homeopathic medicines in primary dysmenorrhea: a double-blind, randomized, placebo-controlled, clinical trial. J Complement Integr Med 2021 Jun 3. doi: 10.1515/jcim-2020-0512. Online ahead of print.

    IndHom  HRI2

  • Teixeira MZ, Podgaec S, Baracat EC (2017). Potentized estrogen in homeopathic treatment of endometriosis-associated pelvic pain: A 24-week, randomized, double-blind, placebo-controlled study. European Journal of Obstetrics & Gynecology and Reproductive Biology211: 48–55.                            E
    EnkHom HRI2

     

    • Rossignol, M. et al. Impact of physician preferences for homeopathic or conventional medicines on patients with musculoskeletal disorders: results from the EPI3-MSD cohort. Drug Saf., 2012; 21: 1093–1101 | PubMed
      cohort studie
    • Bell I, Lewis D, Brooks A, Schwartz G, Lewis S, Walsh B, Baldwin C (2004). Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo. Rheumatology; 43: 577–582.       

     

  • Chapman EH, Weintraub RJ, Milburn MA, Pirozzi TO, Woo E (1999). Homeopathic treatment of mild traumatic brain injury: a randomized, double-blind, placebo-controlled clinical trial. Journal of Head Trauma Rehabilitation; 14: 521–542.                                                                         HRI2

     

  • Frass M, Lechleitner P, Gründling C, Pirker C, Grasmuk-Siegl E, Domayer J, Hochmair M, Gaertner K, Duscheck C, Muchitsch I, Marosi C, Schumacher M, Zöchbauer-Müller S, Manchanda RK, Schrott A, Burghuber O (2020). Homeopathic Treatment as an Add-On Therapy May Improve Quality of Life and Prolong Survival in Patients with Non-Small Cell Lung Cancer: A Prospective, Randomized, Placebo-Controlled, Double-Blind, Three-Arm, Multicenter Study. Oncologist; 25(12): e1930-e1955.                           HRI2

    • Ferley JP, Zmirou D, D’Adhemar D, Balducci F (1989). A controlled evaluation of a homoeopathic preparation in the treatment of influenza like syndromes. British Journal of Clinical Pharmacology; 27: 329–335.                                       .                                                                                                          EnkHom    HRI2 
    • Ghosh P, Ganguly S, Mukherjee SK, Dutta S, Shaikh AR, Ali SS, Singh NK, Bhattacharya P, Koley M, Saha S. Individualized Homeopathic Medicines in Treatment of Hyperuricemia: Evaluation by Double-Blind, Randomized, Placebo-Controlled Trial. Homeopathy 2022 Sep 19. doi: 10.1055/s-0042-1751272. Online ahead of print. 
      IndHom      HRI2
    • Papp R, Schuback G, Beck E, Burkard G, Bengel J, Lehrl S, Belon P (1998). Oscillococcinum® in patients with influenza-like syndromes: a placebo-controlled double-blind evaluation. British Homoeopathic Journal; 87: 69–76.
      EnkHom   HRI2
    • Ferley JP, Zmirou D, D’Adhemar D, Balducci F (1989). A controlled evaluation of a homoeopathic preparation in the treatment of influenza like syndromes. British Journal of Clinical Pharmacology; 27: 329–335.       
      HRI2

     

      • Bronchiaal astma                                                                                                1 pos RCT

    Qutubuddin M, Murty Singh S, Nayak C, Koley M, Saha S (2019). Efficacy of individualized homeopathy in bronchial asthma in adults: Double-blind, randomized, placebo-controlled, clinical trial in the context of usual care. Advances in Integrative Medicine; 6(2): 58–65.                            IndHom   

    • Sinusitis    Zie:    Hard bewijs 
    • Acute otitis media, acute middenoorontsteking. (HRI)                 3 pos RCT

    Sinha, MN et al. Randomized controlled pilot study to compare Homeopathy and Conventional therapy in Acute Otitis Media. Homeopat. J. Fac. Homeopat., 2012; 101: 5–12 | PubMed                                                 HRI

    • Haidvogl M. et al. Homeopathic and conventional treatment for acute respiratory and ear complaints: A comparative study on outcome in the primary care setting. BMC Complement and Altern Med, 2007; 7:7 | Full text
    • Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial. Pediatr Infect Dis J., 2001; 20(2): 177-83 | PubMed                                                           HRI2
    • Acute hoest bij luchtweginfecties                                                               2 pos RCT

    Zanasi A, Mazzolini M, Tursi F, Morselli-Labate AM, Paccapelo A, Lecchi M (2014). Homeopathic medicine for acute cough in upper respiratory tract infections and acute bronchitis: A randomized, double-blind, placebo-controlled trial. Pulmonary Pharmacology & Therapeutics; 27(1): 102–108.                       H                                                                                                                                                 HRI2

    • Voß HW, Michalsen A, Brünjes R (2018). Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough-A double-blind, placebo-controlled, clinical trial. Drug Research (Stuttg); 68(8): 444–449.

                                                                                                                               CompHom          HRI2

    • Luchtweg infecties                                                           2 pos RCT, 1 cohort studie

    Grimaldi-Bensouda, L. et al. Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008. PLoS One, 2014; 9: e89990 | Full text                      cohort studie

    • Jacobs J, Taylor JA (2016). A randomized controlled trial of a homeopathic syrup in the teatment of cold symptoms in young children. Complementary Therapies in Medicine; 29: 229–234.                              HRI2
    • Diefenbach M, Schilken J, Steiner G, Becker HJ (1997). Homöopathische Therapie bei Erkrankungen der Atemwege. Auswertung einer klinischen Studie bei 258 Patienten [Homeopathic therapy in respiratory tract diseases. Evaluation of a clinical study in 258 patients]. Zeitschrift für Allgemeinmedizin; 73: 308–314.                                                                        HRI2
    • Tonsillitis, amandelontsteking                                                                      1 pos RCT

    Malapane E, Solomon EM, Pellow J (2014). Efficacy of a homeopathic complex on acute viral tonsillitisJournal of Alternative and Complementary Med; 20(11): 868–873.                                                                              CompHom   HRI2

    • Overmatige afscheiding luchtwegen

    Frass M, Dielacher C, Linkesch M, Endler C, Muchitsch I, Schuster E, Kaye A (2005). Influence of potassium dichromate on tracheal secretions in critically ill patients. Chest; 127: 936–941.                                                          EnkHom    HRI2

    • Snurken     1 pos RCT

    Lipman D, Sexton G, Schlesser J (1999). A randomized double-blind placebo-controlled evaluation of the safety and efficacy of a natural over-the-counter (OTC) medication in the management of snoring. Sleep and Breathing; 3: 53–56.                                                                                                                             EnkHom HRI2

    • Influenza, griepbeelden    4 pos RCT
    • Ferley JP, Zmirou D, D’Adhemar D, Balducci F (1989). A controlled evaluation of a homoeopathic preparation in the treatment of influenza like syndromes. British Journal of Clinical Pharmacology; 27: 329–335.                                       .                                                                                                                                EnkHom    HRI2 
    • Ghosh P, Ganguly S, Mukherjee SK, Dutta S, Shaikh AR, Ali SS, Singh NK, Bhattacharya P, Koley M, Saha S. Individualized Homeopathic Medicines in Treatment of Hyperuricemia: Evaluation by Double-Blind, Randomized, Placebo-Controlled Trial. Homeopathy 2022 Sep 19. doi: 10.1055/s-0042-1751272. Online ahead of print.                                                             IndHom      HRI2
    • Papp R, Schuback G, Beck E, Burkard G, Bengel J, Lehrl S, Belon P (1998). Oscillococcinum® in patients with influenza-like syndromes: a placebo-controlled double-blind evaluation. British Homoeopathic Journal; 87: 69–76.

                                                                                                                                                             EnkHom   HRI2

    • Ferley JP, Zmirou D, D’Adhemar D, Balducci F (1989). A controlled evaluation of a homoeopathic preparation in the treatment of influenza like syndromes. British Journal of Clinical Pharmacology; 27: 329–335.        HRI2
    • Vertigo, duizeligheid                                                         1  meta-analyse

    Schneider et al. Treatment of vertigo with a homeopathic complex remedy compared with usual treatments – a meta-analysis of clinical rials. Arzneim.-Forschung, 2005; 55(1): 23-29 | PubMed                               Meta-analyse      Fac

    • Grimaldi-Bensouda, L. et al. Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008. PLoS One, 2014; 9: e89990 | Full text                      cohort studie
    • Jacobs J, Taylor JA (2016). A randomized controlled trial of a homeopathic syrup in the teatment of cold symptoms in young children. Complementary Therapies in Medicine; 29: 229–234.                              HRI2
    • Diefenbach M, Schilken J, Steiner G, Becker HJ (1997). Homöopathische Therapie bei Erkrankungen der Atemwege. Auswertung einer klinischen Studie bei 258 Patienten [Homeopathic therapy in respiratory tract diseases. Evaluation of a clinical study in 258 patients]. Zeitschrift für Allgemeinmedizin; 73: 308–314.                                                                        HRI2

     

  • Menopausaal  syndroom, overgangsklachten

    • Macías-Cortés ED et al. Individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP study): a randomized, double-dummy, double-blind, placebo-controlled trial. PLoS One, 2015 ;10(3):e0118440 | Full text  HRI2
    • Gupta J, Kulshreshtha D, Lamba CD, Gupta P, Shinde V, Wadhwa B, Soren A, Arya JS, Koley M, Pramanik A, Parveen S, Kumar A (2019). Homoeopathic medicine – Sepia for the management of menopausal symptoms: A multicentric, randomised, double-blind placebo-controlled clinical trial. Indian J Res Homoeopathy; 13: 219-228.
      EnkHom  HRI2 
    • Colau JC, Vincent S, Marijnen P, Allaert FA (2012). Efficacy of a non-hormonal treatment, BRN-01, on menopausal hot flashes: a multicenter, randomized, double-blind, placebo-controlled trial. Drugs R D; 12(3): 107–119. 
      C
      CompHom   HRI2
    • Andrade DCDS, Carmona F, Angelucci MA, Martinez EZ, Pereira AMS (2019). Efficacy of a homeopathic medicine of Capsicum frutescens L. (Solanaceae) in the treatment of hot flashes in menopausal women: a phase-2 randomized controlled trial. Homeopathy; 108(2): 102–107.      EnkHom  HRI2
    • Jonas WB, Linde K, Ramirez G. Homeopathy and rheumatic  dis. Rheumatic Disease Clinics of North America, 2000; 26: 117–123. 
      review Fac

    • Morris M, Pellow J, Solomon EM, Tsele-Tebakang T (2016). Physiotherapy and a homeopathic complex for chronic low-back pain due to osteoarthritis: a randomized, controlled pilot study. Alternative Therapies in Health and Medicine; 22: 48–56.
      ComplHom    HRI2

    • Lozada CJ, del Rio E, Reitberg DP, Smith RA, Kahn CB, Moskowitz RW (2017). A double-blind, randomized, saline-controlled study of the efficacy and safety of co-administered intra-articular injections of Tr14 and Ze14 for treatment of painful osteoarthritis of the knee: The MOZArT trial. European Journal of Integrative Medicine: 13: 54–63.
      CompHom  HRI2

    • Bhattacharyya S, Chatterjee C, Saha S, Naskar S, Bhattacharya P, Alam SM, Sengupta S, Ahamed S, Shaikh AR, Koley M, Ghosh P, Mukherjee SK (2023). Individualized Homeopathic Medicines in the Treatment of Knee
      Osteoarthritis: Double-Blind, Randomized, Placebo-Controlled Feasibility Trial. Homeopathy. Sep 25. doi: 10.1055/s-0043-1771025. Online ahead of print.
      IndHom   HRI2

       

  • Frass M, Dielacher C, Linkesch M, Endler C, Muchitsch I, Schuster E, Kaye A (2005). Influence of potassium dichromate on tracheal secretions in critically ill patients. Chest; 127: 936–941.                                                          EnkHom    HRI2

    • Clark J, Percivall A (2000). A preliminary investigation into the effectiveness of the homeopathic remedy, Ruta graveolens, in the treatment of pain in plantar fasciitis. British Journal of Podiatry3: 81–85.          
      EnkHom    HRI2
    • Shahid S, Ghosh S, Chakraborty AS, Maiti S, Sadhukhan S, Koley M, Saha S. Efficacy of Individualized Homeopathic Medicines in Plantar Fasciitis: Double-blind, Randomized, Placebo-Controlled Clinical Trial. Homeopathy 2021 Sep 07. DOI: 10.1055/s-0041-1731383. Online ahead of print.
      IndHom  HRI2
    • Seeley BM, Denton AB, Ahn MS, Maas CS (2006). Effect of homeopathic Arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo-controlled clinical trial. Archives of Facial Plastic Surgery; 8: 54–59.                                                                                                                EnkHom     HRI2
    • Robertson A, Suryanarayanan R, Banerjee A (2007). Homeopathic Arnica montana for post-tonsillectomy analgesia: a randomised placebo control trial. Homeopathy; 96: 17–21.                                                              
      EnkHom     HRI2
    • [37] Barnes J, Resch K-L, Ernst E. Homeopathy for postoperative ileus? A meta-analysis. Journal of Clinical Gastroenterology, 1997; 25: 628–633.
      Meta-analyse  Fac
  • Oberbaum M, Galoyan N, Lerner-Geva L, Singer SR, Grisaru S, Shashar D, Samueloff A (2005). The effect of the homeopathic remedies Arnica and Bellis perennis on mild postpartum bleeding – a randomized, double-blind, placebo-controlled study – preliminary results. Complementary Therapies in Medicine; 13: 87–90.                                                                                 EnkHom  HRI2

  • Berrebi A, Parant O, Ferval F, Thene M, Ayoubi JM, Connan L, Belon P (2001). Traitement de la douleur de la montée laiteuse non souhaitée par homéopathie dans le postpartum immédiat [Treatment of pain due to unwanted lactation with a homeopathic preparation given in the immediate post-partum period]. Journal de gynécologie, obstétrique et biologie de la reproduction; 30: 353–357.                                                                      EnkHom   HRI2

    • Yakir M, Kreitler S, Brzezinski A, Vithoulkas G, Oberbaum M, Bentwich Z (2001). Effects of homeopathic treatment in women with premenstrual syndrome: a pilot study. British Homeopathic Journal; 90: 148–153.
      H
      HRI2
    • Yakir M, Klein-Laansma CT, Kreitler S, Brzezinski A, Oberbaum M, Vithoulkas G, Bentwich Z (2019). A placebo-controlled double-blind randomized trial with individualized homeopathic treatment using a symptom cluster approach in women with premenstrual syndrome. Homeopathy; 108(4): 256–269. 
      HRI2        
    • Klein-Laansma CT, Jong M, von Hagens C, Jansen JPCH, van Wietmarschen H, Jong MC. Semi-Individualized Homeopathy Add-On Versus Usual Care Only for Premenstrual Disorders: A Randomized, Controlled Feasibility Study. J Altern Complement Med. 2018 Mar 22. doi: 10.1089/acm.2017.0388.

             Hom.nl

    • Klein-Laansma CT, Jansen JCH, Van Tilborgh AJW and Van Vliet M. Evaluation of Semi Standardized Individualized Homeopathic Treatment of 77 Women with Premenstrual Disorders: Observational Study with 9 Months Follow-Up, Altern Integ Med 2014, 3:3. http://dx.doi.org/10.4172/2327-5162.1000164
      Observatie studie   Hom.nl
    • Klein-Laansma CT, Jansen JC, van Tilborgh AJ, Van der Windt DA, Mathie RT, Rutten AL. Semi-standardised homeopathic treatment of premenstrual syndrome with a limited number of medicines: feasibility study. Homeopathy. 2010 Jul;99(3):192-204.doi:10.1016/j.homp.2010.05.007.
      Hom.nl

    Hom.nl = https://homeopathie.nl/onderzoek-pms/

     

    • Das AD, Ghosh S, Palanisamy C, Guha N, Mandal S, Maiti S, Nath A, Singh NK, Koley M, Saha S. Efficacy of individualized homeopathic medicines in irritable bowel syndrome: A double-blind randomized, placebo-controlled trial. Explore (NY) 2022 Oct 19;S1550-8307(22)00169-0. doi: 10.1016/j.explore.2022.10.004. Online ahead of print.
      IndHom  HRI2
    • Rahlfs VW, Mössinger P (1978). Asa foetida bei Colon irritabile – Doppelblindversuch [Asa foetida in the treatment of the irritable colon – a double-blind trial]. Deutsche medizinische Wochenschrift; 104: 140–143.
      EnkHom  HRI2
    • Balamurugan D, Nayak C, Chattopadhyay A, Karuppusamy A, Ambrose MM, Kumar A, Singh NK, Koley M, Saha S (2023). Individualized Homeopathic Medicines in the Treatment of Psoriasis Vulgaris: Double-Blind,
      Randomized, Placebo-Controlled Trial. Complement Med Res. 30(4): 317-331.                                                                                                                  IndHom HRI2
    • Bernstein S, Donsky H, Gulliver W, Hamilton D, Nobel S, Norman R (2006). Treatment of mild to moderate psoriasis with Reliéva, a Mahonia aquifolium extract – a double-blind, placebo-controlled study. American Journal of Therapeutics; 13: 121-126.                                                                  EnkHom   HRI2
  • Balzarini A, Felisi E, Martini A, De Conno F (2000). Efficacy of homeopathic treatment of skin reactions during radiotherapy for breast cancer: a randomized, double-blind clinical trial. British Homeopathic Journal89: 8–12.                                                                                                                        EnkHom  HRI2

  • Balzarini A, Felisi E, Martini A, De Conno F (2000). Efficacy of homeopathic treatment of skin reactions during radiotherapy for breast cancer: a randomized, double-blind clinical trial. British Homeopathic Journal89: 8–12.                                                                                                                         EnkHom  HRI2

  • Frass M, Linkesch M, Banyai S, Resch G, Dielacher C, Lobl T, Endler C, Haidvogl M, Muchitsch I, Schuster E (2005). Adjunctive homeopathic treatment in patients with severe sepsis: a randomized, double-blind, placebo-controlled trial in an intensive care unit. Homeopathy; 94: 75–80.                                             HRI2

  • Sinusitis 
    Zie:    Hard bewijs 

    • Grimaldi-Bensouda, L. et al. Management of upper respiratory tract infections by different medical practices, including homeopathy, and consumption of antibiotics in primary care: the EPI3 cohort study in France 2007-2008. PLoS One, 2014; 9: e89990 | Full text                       Cohort studie
    • Friese K-H, Zabalotnyi DI (2007). Homöopathie bei akuter Rhinosinusitis. Eine doppelblinde, placebokontrollierte Studie belegt die Wirksamkeit und Verträglichkeit eines homöopathischen Kombinations-arzneimittels [Homeopathy in acute rhinosinusitis. A double-blind, placebo controlled study shows the efficiency and tolerability of a homeopathic combination remedy]. HNO; 55: 271–277.                                                                 CompHom     HRI2
    • Zabolotnyi DI, Kneis KC, Richardson A, Rettenberger R, Heger M, Kaszkin-Bettag M, Heger PW (2007). Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. Explore (NY); 3: 98–109.                                                                                                                                CompHom     HRI2
    • Weiser M, Clasen B (1994). Randomisierte plazebokontrolierte Doppelblindstudie zur Untersuchung der klinische Wirksamkeit der homöopathischen Euphorbium compositum-Nasentropfen S bei chronischer Sinusitis [Randomized, placebo-controlled, double-blind study of the clinical efficacy of the homeopathic Euphorbium compositum-S nasal spray in cases of chronic sinusitis]. Forschende Komplementärmedizin; 1: 251–259.                                                                                                                                   E                                                                                                                               EnkHOm  HRI2
    • Michalsen A, Palm J, Samer H, Wollmann J-C, Tausend S, Klein I, Schnitker J (2017). Wirksamkeit und Verträglichkeit eines homöopathischen Komplexmittels (Sinusitis Hevert SL) bei akuter, unkomplizierter Rhinosinusitis: Eine multizentrische, randomisierte, doppelblinde, placebokontrollierte Studie an erwachsenen Patienten. [Efficacy and Safety of a Complex Homeopathic Remedy (Sinusitis Hevert SL) Used in Acute, Uncomplicated Rhinosinusitis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial in Adults]. Complementary Medicine Research; 24(3): 139–146.     CompHom  HRI2

     

    • Grimaldi-Bensouda, L. et al. Who seeks primary care for sleep, anxiety and depressive disorders from physicians prescribing homeopathic and other complementary medicine? Results from the EPI3 population survey. BMJ Open, 2012; 2 | Full text                                                                                Cohort studie

    • Kolia-Adam N, Solomon E, Bond J, Deroukakis M (2008). The efficacy of Coffea cruda on insomnia: a double blind trial. Simillimum; 21: 91–99.  EnkHom

    • Michael J, Singh S, Sadhukhan S, Nath A, Kundu N, Magotra N, Dutta S, Parewa M, Koley M, Saha S (2019). Efficacy of individualized homeopathic treatment of insomnia: Double-blind, randomized, placebo-controlled clinical trial. Complementary Therapies in Medicine; 43: 53–59.             HRI2

    • Naudé DF, Couchman IMS, Maharaj A (2010). Chronic primary insomnia: efficacy of homeopathic simillimum. Homeopathy; 99: 63–68.               HRI2

       

      •  
  • Lipman D, Sexton G, Schlesser J (1999). A randomized double-blind placebo-controlled evaluation of the safety and efficacy of a natural over-the-counter (OTC) medication in the management of snoring. Sleep and Breathing; 3: 53–56.                                                                                                                             EnkHom HRI2

  • Referenties bij TonsillitisMalapane E, Solomon EM, Pellow J (2014). Efficacy of a homeopathic complex on acute viral tonsillitis. Journal of Alternative and Complementary Med; 20(11): 868–873.                                                                              CompHom   HRI2

  • Cavalcanti AM, Rocha LM, Carillo R Jr, Lima LU, Lugon JR (2003). Effects of homeopathic treatment on pruritus of haemodialysis patients: a randomized placebo-controlled double-blind trial. Homeopathy; 92: 177–181.
    HRI2

  • Ernst E, Saradeth T, Resch KL (1990). Complementary therapy of varicose veins – a randomized, placebo-controlled, double-blind trial. Phlebology; 5: 157–163.                                                                                                                                HRI2

  • Adler UC, Acorinte AC, Calzavara FO, da Silva AA, de Toledo Cesar A, Adler MS, Martinez EZ, Galduróz JCF (2018). Double-blind evaluation of homeopathy on cocaine craving: a randomized controlled pilot study. Journal of Integrative Medicine; 16(3): 178–184.             HRI2

  • Gerhard I, Pateck A, Monga B, Blank A, Gorkow C (1998). Mastodynon bei weiblicher Sterilitat. Randomisierte, plazenbokontrollierte, klinische oppelblindstudie. [Mastodynon for female infertility. Randomised, placebo controlled, clinical double-blind study]. Forschende Komplementärmedizin5: 272–278.                                                CompHom  HRI2

  • Registratie van homeopathische geneesmiddelen. Sinds 2002 wordt er een onderscheid gemaakt tussen geregistreerde en niet-geregistreerde homeopathische geneesmiddelen. Wat betreft bereiding en werkzaamheid is er geen onderscheid. Aan registratie van een geneesmiddel zijn voor de fabrikant hoge kosten verbonden en alleen zinvol als die kosten in een bepaalde tijd ook weer terugverdiend kunnen worden. Daar het assortiment geneesmiddelen binnen de homeopathie zeer uitgebreid is en van dit assortiment een groot aantal beperkt wordt voorgeschreven, hebben veel fabrikanten er voor gekozen deze niet voor registratie aan te melden. Dit betekent in de praktijk dat ze slechts als magistrale bereiding op recept mogen worden afgeleverd door een apotheek en ze vaak niet voor vergoeding door de ziektekosten verzekeraar in aanmerking komen.Zie website: wetgeving en het gratis boekje (download)  Homeopathica over bereiding van homeopathische geneesmiddelen
  • Onder repertoriseren verstaat men in de homeopathie een bepaalde zoekstrategie bij de geneesmiddelkeus waarbij van een symptomenindex of repertorium gebruik wordt gemaakt. De homeopaat zal na een grondige anamnese, de vele door de patiënt naar voren gebrachte klachten en symptomen ordenen en in een volgorde van belangrijkheid zetten. Die symptomen hebben de grootste waarde die het meest bijzonder en opvallend zijn, vervolgens kenmerkende en duidelijke psychische symptomen, algemene symptomen en als laatst de orgaansymptomatologie of lokale symptomen. Zo kan het zijn dat uit een lange reeks symptomen, slechts 5-10 als meest belangrijke symptomen naar voren komen en vervolgens worden opgezocht in een repertorium. De best scorende geneesmiddelen worden vervolgens in een materia medica nagelezen en een keus gemaakt voor één middel.Zie website: geneesmiddelkeus
  • Een homeopathisch repertorium is een symptomen-index op de materia medica. In de materia medica staan de symptomen per geneesmiddel geordend. In een repertorium staan de symptomen volgens een vast lichaamsschema genoemd met achter elk symptoom de geneesmiddelen, die dat symptoom in hun geneesmiddel-beeld hebben. Voor de practicus is het gebruik van een repertorium zeer behulpzaam bij het bepalen van het best bij de patiënt passend geneesmiddel. Tijdens de ontwikkeling van de homeopathie en uitbreiding van de materia medica zijn er verschillende repertoria ontstaan, allen met eigen kenmerken. Het bekendst zijn het Repertorium van Kent en het Repertorium van von Bönninghausen.Tegenwoordig zijn de repertoria opgenomen in homeopathische software zoals RADAR-Opus of Mc Repertory en Reference Works. Het gebruik van het repertorium kent ook zijn beperkingen. Het blijkt dat met gebruik van moderne statistiek de betrouwbaarheid van een voorschrift veel verbeterd kan worden, meer dan met welk repertorium ook. (L. Rutten cs.)Zie website: geneesmiddelkeus

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